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Placental Abruption

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Placental abruption

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Placental abruption is more common than the other emergencies, with an incidence between 0.5 - 2% of all pregnancies. Data from the West Midlands

Abruptio occurs because of premature separation of a normally sited placenta, with bleeding that may be concealed (33%) or revealed.

 

Associations of placental abruption:

  • Abdominal trauma (Reference1)
  • High parity
  • Hypertension and PET (Reference2)
  • Growth restriction
  • Uterine overdistension
  • Smoking (Reference2)

There is also research into the association of placental abruption with thrombophillias, specifically protein C and the Leiden V mutation (Reference3)

Incidence is 10 times more likely if there is a previous history of abruption (Reference4), and 3 times more likely if there is a history of PROM (Reference5), smoking or hypertension (Reference2).

Most commonly, abruptio presents with a tender and tense uterus, bleeding and the start of contractions (Reference6). However, beware as the abdomen may be soft if the placenta is posterior.

A major abruption needs prompt treatment and delivery to avoid maternal complications and fetal demise.

Emergency treatment of abruption: (Reference7)

Treat the shock

  • Give oxygen
  • Insert intravenous lines
  • Arrange a cross-match of 6 units of blood
  • IV fluids
Deliver the fetus
  • By caesarean section (if fetal distress; fetus viable)
  • By rupturing the membranes (if ripe cervix or fetus nonviable)
Treat DIC
  • Urgent haematological consultation
  • Check platelet count
  • May require FFPs
  • Transfusion

Reference: Chamberlain GC. ABC of labour care - Obstetric emergencies. BMJ 1999;318:1342-5.

 


References:

1. Reis PM, Sander CM, Pearlman MD, Abruptio placentae after auto accidents. A case-control study. J Reprod Med 2000 Jan;45(1):6-10, Abstract

2. Ananth CV, Smulian JC, Vintzileos AM, Incidence of placental abruption in relation to cigarette smoking and hypertensive disorders during pregnancy: a meta-analysis of observational studies. Obstet Gynecol 1999 Apr;93(4):622-8, Abstract

3. Wiener-Megnagi Z, Ben-Shlomo I, Goldberg Y, Shalev E, Related Articles, Resistance to activated protein C and the leiden mutation: high prevalence in patients with abruptio placentae. Am J Obstet Gynecol 1998 Dec;179(6 Pt 1):1565-7, Abstract

4. Ananth CV. Placental abruption and its association with hypertension and prolonged rupture of membranes: a methodological review and meta-analysis. Obstet Gynecol 1996;88(2):309-18, Abstract

5. Major CA. Preterm prolonged rupture of membranes and abruptio placentae: is there an association between these pregnancy complications? Am J Obstet Gynecol 1995;172(2 Pt1):672-6

6. Ananth CV. Incidence of placental abruption in relation to cigarette smoking and hypertensive disorders during pregnancy: a meta-analysis of observational studies. Obstet Gynecol 1999;93(4):622-8, Abstract

7. Chamberlain GC. Steer PJ. ABC of labour care. Obstetric emergencies. BMJ 1999;318:1342, Abstract


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